Which vasopressor should be prioritized in cases of aortic stenosis?

Which vasopressor should be prioritized in cases of aortic stenosis?

• A. Epinephrine
• B. Dopamine
• C. Norepinephrine
• D. Phenylephrine

Answer: (D)

In cases of aortic stenosis, phenylephrine is the preferred vasopressor due to its specific hemodynamic effects. Aortic stenosis leads to left ventricular outflow obstruction, resulting in decreased cardiac output and impaired oxygen delivery to tissues. In this scenario, maintaining systemic vascular resistance is crucial, as it allows for improved perfusion pressure without overloading the heart. Phenylephrine is a selective alpha-1 adrenergic agonist that causes vasoconstriction, resulting in increased systemic vascular resistance and blood pressure. This action helps to support perfusion to vital organs without significantly increasing heart rate or myocardial oxygen demand, which can be detrimental in aortic stenosis patients who already have compromised cardiac function. In contrast, other vasopressors like epinephrine and norepinephrine can increase heart rate and cardiac contractility, potentially exacerbating the underlying problem and worsening the patient's condition. Dopamine has varied effects depending on the dose and may not provide the same targeted vascular resistance benefits as phenylephrine in this specific situation. Therefore, prioritizing phenylephrine helps to manage blood pressure effectively without adding extra cardiac workload.

In cases of aortic stenosis, phenylephrine is the preferred vasopressor due to its specific hemodynamic effects. Aortic stenosis leads to left ventricular outflow obstruction, resulting in decreased cardiac output and impaired oxygen delivery to tissues. In this scenario, maintaining systemic vascular resistance is crucial, as it allows for improved perfusion pressure without overloading the heart.

Phenylephrine is a selective alpha-1 adrenergic agonist that causes vasoconstriction, resulting in increased systemic vascular resistance and blood pressure. This action helps to support perfusion to vital organs without significantly increasing heart rate or myocardial oxygen demand, which can be detrimental in aortic stenosis patients who already have compromised cardiac function.

In contrast, other vasopressors like epinephrine and norepinephrine can increase heart rate and cardiac contractility, potentially exacerbating the underlying problem and worsening the patient's condition. Dopamine has varied effects depending on the dose and may not provide the same targeted vascular resistance benefits as phenylephrine in this specific situation. Therefore, prioritizing phenylephrine helps to manage blood pressure effectively without adding extra cardiac workload.